黎孟枫
“长江学者”特聘教授,中山大学副校长,中山医学院院长
http://www.bio360.net/attachments/character/2016/12/14823889352b48be0117eb2ce8.jpg

研究学习经历:

编辑
主要学术兴趣在于认识炎症过程、肿瘤发生、病原感染三者之间的分子联系,研究与此相关的信号控制机理及其临床意义,特别是其中 NF-kappaB 信号通路所涉及的新调控分子与工作机制;研究 NF-κB 调控分子在肿瘤发生发展和病原重症感染两大类疾病中的临床意义,例如可用于诊断、预后判断的新分子标志物和治疗新靶点。研究中所涉及疾病模型包括脑胶质瘤、肺癌、乳腺癌、重症登革、重症肝炎、重症呼吸道病毒病等。现任国务院学位委员会学科评议组成员,教育部临床医学专业认证专家委员会成员,《The Journal of Gene Medicine》主编,中国微生物学会《病毒学报》副总编辑等学术兼职。

代表性论文:

编辑
  1. Xun Zhu, Zhenjian He, Yiwen Hu, Weitao Wen, Cuiji Lin, Jianchen Yu, Jing Pan, Ran Li, Haijing Deng, Shaowei Liao, Jie Yuan, Jueheng Wu, Jun Li, Mengfeng Li*. MicroRNA-30e* suppresses dengue virus replication by promoting NF-κB–dependent IFN production. PLoS Neglected Tropical Diseases. 8(8):e3088 (published online, totally 8 pages), 2014.
  2. Xun Zhu, Zhenjian He, Jie Yuan, Weitao Wen, Xuan Huang, Yiwen Hu, Cuiji Lin, Jing Pan, Ran Li, Haijing Deng, Shaowei Liao, Rui Zhou, Jueheng Wu, Jun Li, Mengfeng Li*. IFITM3-containing exosome as a novel mediator for anti-viral response in dengue virus infection. Cellular Microbiology. In press, 2014.
  3. Junchao Cai, Hongyu Guan, Lishan Fang, Yi Yang, Xun Zhu, Jie Yuan, Jueheng Wu and Mengfeng Li *. MicroRNA-374a activates Wnt/β-catenin signaling to promote breast cancer metastasis. The Journal of Clinical Investigation.123(2):566-579. 2013
  4. Zhe Ying, Yun Li, Jueheng Wu, Xun Zhu, Yi Yang, Han Tian, Wei Li, Bo Hu, Shi-Yuan Cheng, Mengfeng Li*. Loss of miR-204 Expression Enhances Glioma Migration and Stem Cell-Like Phenotype. Cancer Research. 73(2): 990-999. 2013.
  5. Junchao Cai, Jueheng Wu, Huizhong Zhang, Lishan Fang, Yongbo Huang, Yi Yang, Xun Zhu, Rong Li, Mengfeng Li*. MiR-186 Downregulation Correlates with Poor Survival in Lung Adenocarcinoma, Where It Interferes with Cell-Cycle Regulation. Cancer Research. 73(2):756-766. 2013
  6. Junchao Cai, Lishan Fang, Yongbo Huang, Rong Li, Jie Yuan, Yi Yang, Xun Zhu, Baixue Chen, Jueheng Wu, Mengfeng Li*. MiR-205 targets PTEN and PHLPP2 to augment AKT signaling and drive malignant phenotypes in non-small cell lung cancer. Cancer Research. 73(17):5402-5415. 2013.
  7. Lili Jiang, Chuyong Lin, Libing Song, Jueheng Wu, Baixue Chen, Zhe Ying, Lishan Fang, Xiao Yan, Mian He, Jun Li*, Mengfeng Li*. MicroRNA-30e* promotes human glioma cell invasiveness in an orthotopic xenotransplantation model by disrupting the NF-κB/IκBα negative feedback loop. The Journal of Clinical Investigation. 122(1):33-47. 2012
  8. Hongyu Guan, Heng Zhang, Jueheng Wu, Jie Yuan, Zhengsong Huang* and Mengfeng Li*. IKBKE is overexpressed in glioma and contributes to resistance of glioma cells to apoptosis via activating NF-κB. Journal of Pathology. 223: 436–445. 2011

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