第四届发育与疾病表观遗传学国际研讨会 9 月 18-21 日 中国上海

2018-09-18 至 2018-09-21 中国 上海 上海 徐汇区 | 上海 复制 主委会 18516613552 复制 chris.zhang@bio360.net  复制 http://i.bio360.net/MEET/2018epigenetics/

生物 360 邀您共享表观遗传学研究饕餮盛宴 “第四届发育和疾病的表观遗传学上海国际研讨会 (2018 年 9 月 18-21 日,上海),点击注册

http://i.bio360.net/MEET/2018epigenetics/sign.html

表观遗传学 (Epigenetics) 是论及决定细胞时代间基因组 转录记忆 的与 DNA 序列改变无关的信号, 介导者和机制的学科。表观遗传事件通过对 DNA 和组蛋白的 共价修饰 , 以转录的 RNA 和翻译的蛋白的方式, 调节和功能化地展示编码在 DNA 序列中遗传的结构信息, 继而产生在 时空多维空间 无限多样的表型。健康表观遗传稳态是确保高等生物发育过程中细胞分化和谱系化正常开展所依据的优态基因组表达的必要前提。基因组表观遗传信息界面的异常是包括肿瘤, 代谢类和神经系统疾病在内的疾患的病因, 病理学机制之一。

为了加大本次大会学术交流的力度, 除了 6 个主题 /36 个 25 分钟报告以外, 我们还安排了 12 个 10 分钟报告, 后者是从两个时长 1.5 小时的墙报摘要者中遴选出来的。欢迎各位与会者积极报名并提交墙报摘要!

会议主题:

主题 1. DNA 修饰的化学和生物学

主题 2. 组蛋白修饰的化学和生物学

主题 3. 转录的化学生物学和表观调控

主题 4. 临床表观遗传学

主题 5. 染色质高级结构的化学和生物学

主题 6. 发育的表观遗传学

演讲嘉宾:

徐国良(中科院上海生命科学研究院)

报告题目:A vitamin C-derived DNA modification

http://i.bio360.net/MEET/2018epigenetics/customer.html

朱冰 (中科院生物物理研究所)

报告题目:Dynamic regulation of DNA methylation

http://i.bio360.net/MEET/2018epigenetics/bingzhu.html

James Shen(Academia Sinica,Taipei)

报告题目:Active DNA Demethylation by VertebrateDNA Methyltransferases

http://i.bio360.net/MEET/2018epigenetics/james.html

伊成器(北京大学)

报告题目:Chemical-assisted Sequencing ofEpigenetic Nucleic Acid Modifications

http://i.bio360.net/MEET/2018epigenetics/chengqi.html

张鹍 (UCSD)

报告题目:Single-cell multi-omic analysis of humanorgans.

http://i.bio360.net/MEET/2018epigenetics/kunzhang.html

徐彦辉(复旦大学)

报告题目:Structural Insight into dynamicregulation of DNA methylation

http://i.bio360.net/MEET/2018epigenetics/yanhui.html

Naoko Hattori(Japan)

报告题目:Epigenome Reprogramming as a Basis for Combination Therapy

http://i.bio360.net/MEET/2018epigenetics/naoko.html

刘峰 (中科院动物所)

报告题目:EpigeneticRegulation of Hematopoietic Stem Cell Development

http://i.bio360.net/MEET/2018epigenetics/fengliu.html

陈玲玲 (中科院上海生命科学研究院)

报告题目:THE DIVERSITY AND FUNCTION OF LONG NONCODING RNAS

http://i.bio360.net/MEET/2018epigenetics/lingling.html

沈晓骅 (清华大学)

报告题目:Cis-acting lncRNAs intranscription and chromatin regulation

http://i.bio360.net/MEET/2018epigenetics/xiaohua.html

孙前文(清华大学)

报告题目:R-loop, the general chromatin feature in Arabidopsis genomes

http://i.bio360.net/MEET/2018epigenetics/qianwen.html

王泽峰(中科院上海生命科学研究院)

报告题目:Re-thinking the codingcapacity of non-coding RNA.

http://i.bio360.net/MEET/2018epigenetics/zefeng.html

Hsueh-Ping Chu(National Taiwan University)

报告题目:A long noncoding RNA in telomere maintenance,gene regulation and inter-chromosomal pairing.

http://i.bio360.net/MEET/2018epigenetics/hsueh.html

Yutaka Kondo(Japan)

报告题目:Implication of Long Non-coding RNAs in CancerBiology

http://i.bio360.net/MEET/2018epigenetics/yutaka.html

韩为东 (301 医院)

报告题目:Enhanced anti-tumoractivity of PD1 blockade by DNA demethylating agent in the clinic

http://i.bio360.net/MEET/2018epigenetics/weidong.html

JungKyoon Choi(Singapore)

报告题目:Functional prediction of causal regulatory variants identifies a novelautism gene

http://i.bio360.net/MEET/2018epigenetics/jungkyoon.html

陆星宇(上海)

报告题目:DNA 5-Hydroxymethylcytosines from Cell-freeCirculating DNA as Diagnostic Biomarkers for Human Cancers

http://i.bio360.net/MEET/2018epigenetics/xinyu.html

罗成 (中科院上海药物研究所)

报告题目:Drugdiscovery of protein-protein interactions by targeting epi-modification site ofuntargetable protein

http://i.bio360.net/MEET/2018epigenetics/chengluo.html

李国红(中科院生物物理所)

报告题目:Dynamic regulation ofhigher-order chromatin structures in gene regulation

http://i.bio360.net/MEET/2018epigenetics/guohong.html

颉伟 (清华大学)

报告题目:Reprogramming ofchromatin architecture in early mammalian development

http://i.bio360.net/MEET/2018epigenetics/weixie.html

Yijun Ruan(Jackon Lab)

报告题目:Combinatorial mechanisms in3D genome folding and transcription regulation

http://i.bio360.net/MEET/2018epigenetics/yijun.html

Sheng Zhong(UCSD)

报告题目:Systematic Mapping of RNA-ChromatinInteractions In Vivo

http://i.bio360.net/MEET/2018epigenetics/zhongshen.html

Chandrima Das(India )

报告题目:Decoding the EpigeneticLandscape by the Histone Readers: Implications in human diseases

http://i.bio360.net/MEET/2018epigenetics/chandrima.html

Li-Jung Juan(Academia Sinica,Taipei)

报告题目:CROSSTALK OF N-A-ACETYLTRANSFERASE AND DNAMETHYLATION IN DEVELOPMENT AND DISEASE

http://i.bio360.net/MEET/2018epigenetics/lijung.html

汤富酬(北京大学)

报告题目:Single-cellmulti-omics sequencing of mouse early embryos and embryonic stem cells

http://i.bio360.net/MEET/2018epigenetics/fuchou.html

邓宏魁(北京大学)

报告题目:SmallMolecule-induced Cell Fate Reprogramming

http://i.bio360.net/MEET/2018epigenetics/hongkui.html

大会日程:

19th, Sept, 2018
8:30-8:40Opening
I.Chemical and Biological Perspectives of DNA ModificationsChair of the first half part: Kazu Ushijima (Tokyo)
8:40-9:05A vitamin C-derived DNA modificationGuoliang Xu(Academia Sinica, Shanghai)
9:05-9:25Dynamic regulation of DNA methylationBing Zhu(Academia Sinica, Beijing)
9:25-9:50Active DNA Demethylation by Vertebrate DNA MethyltransferasesJames Shen(Academia Sinica, Taipei)
9:50-10:15Chemical-assisted Sequencing of Epigenetic Nucleic Acid ModificationsChengqi Yi(Peking University)
10:15-10:40Break+Group Photograph
Chair of the second half part : Fei Lan(FuDan University)
10:40-11:05Single-cell multi-omic analysis of human organsKun Zhang(UCSD)
11:05-11:30Structural Insight into dynamic regulation of DNA methylationYanhui Xu (Fudan University)
11:30-11:40Epigenome Reprogramming as a Basis for Combination TherapyNaoko Hattori(Tokyo,Japan)
11:40-11:50Short Talk 2
11:50-13:00Lunch
13:00-14:30Poster session I
II.Chemical and Biological Perspectives of histone modificationsChair of the first half part : Youngjun Kim(Korea, Seul)
14:30-14:55Structure and Function of YEATS Domain in Health and DiseaseHaitao Li(Tsinghua University),
14:55-15:20The Dynamic Regulation of Histone MethylationFei Lan(Fudan University)
15:20-15:45 De-acetylation and Epigenomic regulation

Ullas Kolthur-Seetharam

(Tata Institute, India)
15:45-16:10Metabolic regulation of gene expressionZhimin Lu(MD Anderson)
16:10-16:30Tea Break
Chair of the second half part: Lijung Juan(Academia Sinica, Taipei)
16:30-16:55Epgenetics and Adipogenesis: Implications of Histone modifications LanguagesTapas K. Kundu(India)
16:55-17:20Crosstalk between histone modifications during heterochromatin assemblyJun-ichi Nakayama(Japan)
20th, Sept, 2018
III. Chemical and epigenetic regulation of transcriptionChair of the first half part: Shyam PRABHAKAR (Singapore)
8:30-8:55R-loopsin physiology and pathologyXiangdong Fu(UCSD)
8:55-9:20Epigenetic Regulation of Hematopoietic Stem Cell DevelopmentFeng Liu(Academia Sinica, Beijing)
9:20-9:50The Diversity and Function of Long Noncoding RNAsLingling Chen(Academia Sinica,Shanghai)
9:50-10:15Cis-acting lncRNAs in transcription and chromatin regulationXiaohua Shen(Tsinghua University)
10:15-10:40Tea Break
Chair of the second half part: Hongkui Deng(Peking University)
10:40-11:05R-loop, the general chromatin feature in Arabidopsis genomesQianwen Sun(Tsinghua University)
11:05-11:30Re-thinking the coding capacity of non-coding RNAZefeng Wang(Academia Sinica,Shanghai)
11:30-11:40A long noncoding RNA in telomere maintenance, gene regulation and inter-chromosomal pairingHsueh-Ping Chu (National Taiwan University)
11:40-11:50Short Talk 4
11:50-13:00Lunch
13:00-14:30Poster session 2
IV.Clinical EpigeneticsChair of the first half part : Tapas Kundu(India)
14:30-14:55Implication of Long Non-coding RNAs in Cancer BiologyYutaka Kondo(Nagoya University, Japan)
14:55-15:20Enhanced anti-tumor activity of PD1 blockade by DNA demethylating agent in the clinicWeidong Han(301 Hospital, Beijing);
15:20-15:45Talk 21Teh Bin Tean(Cancer Center, Singapore),
15:45-16:10Functional prediction of causal regulatory variants identifies a novel autism geneJung Kyoon Choi(Korea)
16:10-16:30Tea Break
Chair of the second half part: Zefeng Wang(Academia Sinica)
16:30-16:55DNA 5-Hydroxymethylcytosines from Cell-free Circulating DNA as Diagnostic Biomarkers for Human CancersXingyu Lu(Shanghai)
16:55-17:20Drug discovery of protein-protein interactions by targeting epi-modification state of untargetable proteinCheng Luo(Academia Sinica,Shanghai)
21st, Sept, 2018
V.Chemical and biological perspectives of the higher-order chromatin structureChair of the first half part: Young-Joon Kim(Korea)
8:30-8:55Talk 25Jun-ichi Nakayama(Tokyo,Japan)
8:55-9:20Dynamic regulation of higher-order chromatin structures in gene regulationGuohong Li(Adademia Sinica, Beijing)
9:20-9:45Reprogramming of chromatin architecture in early mammalian developmentWei Xie(Tsinghua University)
9:45-10:10Combinatorial mechanisms in 3D genome folding and transcription regulationYijun Ruan(Jackson Lab, USA)
10:10-10:30Tea Break
Chair of the second half part: Lingling Chen(Academia Sinica, Shanghai)
10:30-10:55Systematic Mapping of RNA-Chromatin Interactions In VivoSheng Zhong(UCSD)
10:55-11:20Talk 30
11:20-11:30Decoding the Epigenetic Landscape by the Histone Readers: Implications in human diseasesChandrima Das
11:30-11:40Short talk 6
11:40-13:00Lunch
VI. Developmental EpigeneticsChair of the first half part: Guoliang Xu(Academia Sinica, Shanghai)
13:00-13:25Talk 31
13:25-13:50CROSSTALK OF N-A-ACETYLTRANSFERASE AND DNA METHYLATION IN DEVELOPMENT AND DISEASELi-Jung Juan(Adademia Sinica,Taipei)
13:50-14:15Single-cell multi-omics sequencing of mouse early embryos and embryonic stem cellsFuchou Tang(Peking University)
14:15-14:25Short talk 7
14:25-14:35Short talk 8
14:35-14:45Short talk 9
14:45-14:55Short talk 10
14:55-15:15Tea Break
Chair of the second half part: Xiangdong Fu(UCSD)
15:40-15:50Short Talk 11
15:50-16:00Short Talk 12
16:00-16:25Talk35
16:25-16:50Small Molecule-induced Cell Fate ReprogrammingHongkui Deng(Peking University)
16:50-17:00Closing

欲实时把握表观遗传学理论、技术和应用的最新进展, 请参加第四届发育和疾病的表观遗传学上海国际研讨会(2018 年 9 月 18-21 日,上海)

会务组

联系人: 张老师 闫老师

邮箱:chris.zhang@bio360.net / event@bio360.net /

电话:021-59555696 / 18516613552 / 18512189851

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